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Clinical studies

Explore our kidney trials and find opportunities to take part in advancing medical research. Listings change as protocols open and close.

Open to Enrollment

Accepting participants

Study-related visits, tests, and investigational therapy are provided at no cost, and your insurance is never billed. Filter by condition to see what may fit.

Enrolling

CKD & High Blood Pressure

Baxdrostat in combination with dapagliflozin, evaluated for renal outcomes and cardiovascular mortality in chronic kidney disease (BaxDuo-Pacific).

Who it is forAdults with chronic kidney disease and high blood pressure.

AstraZeneca·NephrologyAsk about this study
Enrolling

IgA Nephropathy

Extended TARPEYO® (delayed-release budesonide) treatment in adults with primary IgA nephropathy (NefXtend).

Who it is forAdults with primary IgA nephropathy who have completed 9 months of TARPEYO® 16 mg.

Calliditas·NephrologyAsk about this study
Under Way

Active, closed to enrollment

These studies continue with participants already enrolled.

In follow-up

Elevated Lipoprotein(a)

Lepodisiran for cardiovascular risk reduction in adults with high lipoprotein(a) (ACCLAIM-Lp(a)). Enrollment closed; participants are followed through 2029.

Eli Lilly·Cardiorenal
In follow-up

Obesity · Heart & Kidney

Retatrutide's effect on cardiovascular and kidney outcomes in adults living with obesity (TRIUMPH-Outcomes). Enrollment closed; participants are followed through 2029.

Eli Lilly·Cardiorenal
No open or active study matches that condition right now. Tell us anyway. Listings change as protocols open.
Track Record

Twenty-seven completed studies

From the trial programs behind finerenone, dapagliflozin, daprodustat, and tolvaptan to today's next-generation molecules.

  • BayerAlbuminuria in CKD: BAY3283142 (ALPINE 1)
  • BayerNon-diabetic CKD: finerenone (FIND-CKD)
  • Novo NordiskCardiovascular disease and inflammation: ziltivekimab (ZEUS)
  • Regulus TherapeuticsAutosomal dominant polycystic kidney disease (RGLS8429, anti-miR-17)
  • Mineralys TherapeuticsUncontrolled and treatment-resistant hypertension
  • NateraKidney disease diagnosis and management (RenaCARE)
  • Quanta DialysisSelf-care home hemodialysis (Home Run)
  • KBP BioSciencesStage 3b/4 CKD with uncontrolled hypertension
  • AstraZenecaCKD: zibotentan and dapagliflozin (ZENITH-CKD)
  • CloudCathPeritoneal dialysis infection detection
  • AmgenChronic kidney disease
  • BayerKidney failure requiring hemodialysis (osocimab)
  • GSKAnemia of CKD: daprodustat vs darbepoetin alfa
  • BayerType 2 diabetes with diabetic kidney disease (finerenone)
  • BayerCKD progression (finerenone)
  • GSKAnemia associated with chronic kidney disease
  • AstraZenecaCKD: dapagliflozin renal and cardiovascular outcomes
  • MerckIgA nephropathy with persistent proteinuria (atacicept)
  • JanssenType 2 diabetes, CKD and macroalbuminuria (canagliflozin)
  • OtsukaLong-term tolvaptan in ADPKD
  • AmgenSecondary hyperparathyroidism on hemodialysis (etelcalcetide)
  • OtsukaLate-stage CKD due to ADPKD (tolvaptan, REPRISE)
  • AstraZenecaCKD: AZD9977 with dapagliflozin (MIRACLE)
  • Eli LillyMild to moderate diabetic kidney disease (baricitinib)
  • NovartisType 2 diabetes with heart, circulatory and kidney disease
  • NovartisAcute gouty arthritis with frequent flares
  • Hoffmann-La RocheAnemia in non-dialysis CKD
  • AstraZenecaNon-diabetic proteinuria with high cholesterol
  • AstraZenecaDiabetic proteinuria with high cholesterol
  • Johnson & JohnsonAnemia in chronic kidney disease
Next Step

Not sure which study fits?

Tell us a little about your kidney health and the study team will review it against every open protocol, with no cost and no obligation.

  • Participation is always voluntary. Withdraw at any time
  • No cost to you, and your insurance is never billed
  • IRB oversight of every protocol
  • Care delivered by board-certified nephrologists